'A better joint' - Macleans.ca

‘A better joint’

A protein made by the brain acts like marijuana


Scientists in the U.S., have discovered a protein manufactured by the brain that acts like marijuana to relieve pain and stimulate appetite. The protein, known as a peptide, was found in mice. Like another peptide known to bind to the THC receptor affected by marijuana, this peptide does too—and it activates the receptor as well. The researchers hope to develop a drug that activates and blocks the receptor like this new peptide, while avoiding the hazards of marijuana use. Said one: “The next step is for scientists to come up with new medicines that eliminate the nasty side of pot—a better joint, so to speak.”

Science Daily

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‘A better joint’

  1. A peptide Brownie – works for me!

  2. Ummm…..what is the nasty side of pot?

    • haven’t you ever seen Reefer Madness – starts with a joint then you end up in a white slavery ring before you know it!

    • Potential hazards include: addiction, lung disease, temporary impairment (I know the last is the whole point of it for many, but possibly not for those seeking relief from various symptoms), and long term impact on congnative functions.

      • wow you haven’t investigated any of the very many studies that have disproved what you have just stated. (1) The amount of carcinogens in BCBud is way and I mean way less than tobacco and as well there are several recent studies out right now shopwing THC shrinks tumour cells and most efinitely heals Glaucoma = Oh Boy! so one wrong (2) the degree of impairment is way less motor skills wise and plateaus much earlier than almost any other intoxicating substance. (3) Addiction : give me a break after years of either eating brownies or smoking you can put the doobie down and walk away and everything is fine not so with many other substances and I speak from personal experience and have the 12 step program literature to prove it : ask anyone who has been is AA or NA and they are likely to confirm my stand. (4) you can’t overdose on BCBUD : I have tried but after the third toasted peanut butter and jam sandwich you can’t move to light up the next one.

        • That’s why I said potential hazards. I’m not against the stuff, nor was I suggesting it’s evil or anything. But as for your list: Just because the carcinogens are less than tobacco, doesn’t mean they are absent. Impairment may be less than other substances, but it remains the goal of using the stuff (recreationally, anyway). Addiction may be less frequent than with other substances, but it can and does happen (there are convincing studies to this effect, and I’ve personally known folks who had trouble quitting it). I had nothing to say about overdosing, so I have no idea why you brought that up.

          • Googled “coffee carcinogens” and came up with this:

            “Carcinogens are found in many foods–as are offsetting cancer-fighting chemicals–but in small quantities. If we wanted to avoid all carcinogens, we’d have to stop eating altogether. But there are 10 milligrams (mg) of known carcinogens in a single cup of coffee. To put that into perspective, 10 mg is probably more than all the synthetic pesticide residues you could get from eating non-organic food for an entire year. In one cup.”

            Oh, oh.

            But then there was more:

            “Nevertheless, moderate coffee consumption is not considered a risk factor for cancer. And coffee is linked to the following benefits: It boosts endurance by delaying fatigue; it improves long-term memory; it may help prevent kidney stones; it relaxes lung spasms during an asthma episode; and, as you may have discovered, it stimulates your gastrointestinal tract.”

            If pot were legal, there might be a greater chance of it being studied properly from a scientific perspective. And like coffee, we could then decide for ourselves if the side effects of its use, as compared to the risks, were worth indulging in.