Superbugs from South Asia reach Britain - Macleans.ca
 

Superbugs from South Asia reach Britain

Antibiotic-resistant NDM-1 bacteria could spread across globe


 

NDM-1, a gene found in certain bacteria, has scientists worried about a possible pandemic of antibiotic-resistant infections. The gene makes bacteria resistant to every drug on the market and hails from South Asia, where it’s known to inhabit Pakistan, India and Bangladesh. A study published in The Lancet Infectious Diseases journal says medical tourism—both cosmetic and otherwise—will hasten the spread of NDM-1 to Europe and North America. Most of the British patients found with NDM-1-positive infections had traveled to one of two Indian hospitals.

Montreal Gazette


 
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Superbugs from South Asia reach Britain

  1. Alright, I will rephrase that
    "It's always one f*** 'ing thing after another.

  2. Well, I guess we'll just have to wait and see if this thing is really that bad. Until then I'm not going to worry.

  3. Drug resistance has evolved from time immemorial. It has crossed states, countries and continents with increasing travel (may it be for medical tourism or otherwise).
    What makes a micro organism a ‘Superbug' is the genetic makeup of the bacteria. These are usually coded in packets (Plasmids) in the bacteria and are transmitted just like human transmission of genetic mutations. The decoding of these plasmids give insight into the character of the bacteria (how long it will live, how many drugs it is resistant to, how fast they can be transmitted etc) and is similar to gene mapping in humans which tells the character of humans (colour, cancer carriers, genetic disorders, height, how long we will live, will he be diabetic etc).
    Most superbugs can generally be detected in routine standard microbiology labs eg. MRSA (Methicillin resistant Staphylococcus aureus, ESBL (Extended spectrum beta lactamase) in E coli, Klebsiella and others, MBL (metallobetalactamase etc). Research studies can detect special characters (genetic makeup) in such bugs (e.g. in MRSA mecA, in ESBL- CTX-M, IMP, in MBL BlalMP, VIM, NDM-1 etc ) . Routine laboratories anywhere in the world cannot detect such special characters.

    contd

  4. Superbugs are rare but when it occurs it should trigger ANY government, state, health care facility to the following aspects:
    1.Resistance evolves in bacteria due to abuse of antibiotics. (so probably hospital or community physicians are abusing drugs). Abuse of antibiotics occurs usually in the subcontinent and south east asian countries.
    2.Some codes are transmitted by drug feeds in poultry or the food we eat, how close we are with animals can manufacture and these bugs (Again antibiotic abuse).
    3.Regular isolation of the same organism from the same location (hospital, country) can result in outbreaks or epidemics). Outbreaks of this organism can occur if the organism is transmitted quickly usually due to poor infection control practices in the hospitals.
    contd

  5. 4.The hospital should be aware and report such types of bugs both in the interest of the patient and community as a whole.
    5.Its not where these isolates come from but how their transmission can be prevented that is important. Sometimes where it comes from is important as incase of Bioterrorism agents (Anthrax etc)
    6.If increasing Superbugs are seen in a locality they should be tested in research laboratories to know the genetic makeup.
    So don't blame countries. Be scientific not political.
    Learn to develop research facilities that can detect such infections.
    Look into all Hospital systems and Microbiology laboratories to see if facilities are in place to identify and isolate superbugs.
    Finally report these to the international community and the interest of patient care as a whole.
    Dr Godwin Wilson, Clinical Microbiologist (Google me to Contact me)