60-million Indians have gene for early heart disease

Mutated gene effects those in 40s and 50s

Heart disease is a leading killer throughout the world, but it is of particularly grave concern in Indian where 60-million people are estimated to carry a gene that codes for a protein, cardiac myosin-binding protein C. It was found among families with a high incidence of cardiomyopathy, an inflammation of the heart muscle. New research shows that people with one copy of the gene have seven times the chance of developing heart disease, even though they may appear healthy throughout their lives—until age 45, when an abundance of the protein triggers catastrophic results.

Los Angeles Times